It's 1968 and Enoch Powell's infamous 'Rivers of Blood' speech creates serious tension in Poplar, especially when a group of dockers march in support of Powell. The midwives welcome a new nun, Sister Veronica, who's an instant hit with everyone, except Nurse Crane. Meanwhile, Trixie's relationship with Matthew goes from strength to strength, while Nurse Crane helps Nancy with her financial woes. Sister Julienne enjoys helping out on the district rounds,...

Chronicles the lives of a group of midwives who care for expectant mothers in the East End of London in the late-1950s to mid-1960s.

The life and times of a group of midwives working at Nonnatus House--a nursing convent serving the impoverished of East London in the late 1950s and early 1960s--are chronicled in this appealing British series based on true events. The women learn powerful lessons about life's struggles while visiting with expectant mothers and poor children.

Sister Julienne receives a phone call from Holloway Prison where the Salvation Army, who normally provide midwifery for female inmates, have been struck down with influenza. She is called to care for the women and asks Trixie to help her. Shelagh suffers heartbreak when a routine pregnancy check turns out to be something far more serious.

Sister Monica Joan is found wandering near the docks, and returned to Nonnatus House by the police. Her adventure takes its toll on her health and she succumbs to pneumonia. When she eventually recovers she sails forth back into the community only to find

An explosion at the docks brings heartache to the people of Poplar.

The whole Poplar community pulls together to prepare for the annual Summer Fete. This year with the introduction of a Baby Show, the Nonnatus House midwives will be more involved than ever; especially Trixie who assumes responsibility for securing a celebrity judge.

Dr. Turner prepares for change with the introduction of the contraceptive pill, while Patsy struggles to help a Bargee woman who is determined to give birth among her own community. As a huge storm threatens Poplar, Nurse Crane helps save the life of a young mother. After the storm, there is a welcome return for one Nonnatus House resident.

It's 1958 and returning from a long day of duties, Nurse Jenny Lee finds the Nonnatus House community gathered to wish her a happy birthday, before she, Chummy, Trixie and Cynthia head off to the movies. However the midwife's good cheer is short lived when the next day she is assigned a new patient, Molly Brignall, who is trapped in an abusive marriage.

Chummy and PC Noakes meet with new challenges as they settle back down to life in Poplar. Fred is in high spirits when his pregnant daughter, Dolly, and her young son Anthony arrive to stay with him. Jenny's own jubilation comes in the form of potential love interest Alec, a friend and colleague of Jimmy's.